Zadkiel has spent the millennia doing
Heaven's dirty work, fighting hell's incursions onto
Earth and pruning the worst of the worst from the
human population. Over the years, he's come to despise all of humanity, not just the sinners. Now he figures he can do a better job of sitting on the throne of heaven than God. And if he succeeds in his war against heaven, the first order of business will be wiping out the wretched human race.
Zadkiel has come into conflict with God. He believed that he needed the power of the Spirits of Vengeance to help him win his war against hell. Zadkiel revealed to
John Blaze that he was not a
demon of vengeance as he had come to believe due to his being a spirit of vengeance, when actually he is being used as an angel of vengeance. In actuality Roxanne, his old girlfriend, made a deal with Zadkiel, in hopes that she could save Johnny from life time of damnation in hell. However, Zadkiel was easy to persuade he had already declared his own war on heaven. He is attempting to overthrow God himself, and he saw Johnny, or the Ghost Rider, as the ideal pawn to complete his intentions.